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 Past Issues
JAMC 26(2): April-June 2014
CONTENTS
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EDITORIAL |
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- Corruption in healthcare system: An obstacle in
achieving optimal outcome
-
Muhammad Zeeshan Haroon
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109 |
ORIGINAL ARTICLES |
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- TNF-alpha: A risk factor for ischemic stroke
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Faraz
Ahmed Bokhari, Tania A. Shakoori, Ambreen Butt, Farkhanda Ghafoor
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- 111
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- Quantitative analysis of macrophages in
wound healing of rat skin subjected to loud noise stress
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Aisha Rafi, Muhammad Yunus Khan, Liaqat Ali
Minhas
| 115
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- Rheumatoid arthritis: The importance of evidence based
diagnostic reasoning in preventing debilitating consequences
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Naheed Gul, Mujtaba Quadri
| 118 |
- Stroke
after coronary artery bypass surgery with and without cardiopulmonary bypass
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Javed Iqbal, Abdul
Ghaffar, Ahmad Shahbaz, Abdul Rehman Abid
| 123 |
- Frequency of dentofacial asymmetries: A cross-sectional study on
orthodontic patients
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Nita Kumari Bhateja,
Mubassar Fida, Attiya Shaikh
| 129 |
- Isolated
inferior oblique myectomy for hypertropia
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Sadia Bukhari, Ghulam
Qadir Kazi, Umair Qidwai
| 134
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- Efficacy of vancomycin versus linezolid against coagulase-negative Staphylococci
in various clinical
specimens
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Muhammad Murad Ehsan, Ghulam Fatima, M. Owais
Ismail, Zahida Memon
| 137
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- Efficacy and safety of subcutaneous lateral internal sphincterotomy for
chronic anal fissure
- Muhammad Zubair, Muhammad Saaiq, Syed Aslam Shah
| 141
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- Outpatient endometrial biopsy
with Pipelle vs diagnostic dilatation and curettage
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Raazia Rauf, Asma Shaheen, Shamsunisa Sadia, Faressa Waqar, Shamsa Zafar,
Saadia Sultana, Shumaila Waseem
| 145
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- Frequency of albuminuria
in diabetic patients presenting with macrovascular complications
- Muhammad
Sohail, Fozia Fatima, Sadia Fatima, Shahbaz Ali Khan, Syed Abbas Anwar,
Muhammad Adeel Alam, Munir Ahmad Abbasi
| 149
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- Comparison of primary wound closure with delayed
primary closure in perforated appendicitis
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Mukhtar Ahmad,
Kishwar Ali, HumeraLatif, SamanNaz, Khalid Said
| 153
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- Financial
costs to institution on patients waiting for gall bladder disease surgery and
how to reduce them
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Ahmed Waqas, Shahzad Ahmed Qasmi, Faran Kiani, Ahmed Raza, Khizar
Ishtiaque Khan, Shazia Manzoor
| 158
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- Current
trends in undergraduate medical and dental research: A picture from Pakistan
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Waqar Jeelani, Sanaa Masood Aslam, Asrar Elahi
| 162 |
- Impact
of body mass index on left ventricular mass
- Munir Ahmad Rashid,
Bilal Ahsan Qureshi, Nisar Ahmed, Mubasher Ali Sherwani
| 167 |
- Knowledge, attitudes and practices of parents
regarding antibiotic use in children
- Saad Siddiqui, Mubeen Sultan Cheema, Romana Ayub, Noreen Shah, Ameer
Hamza, Sheraz Hussain, Muhammad Hamza Khan, Syed Musa Raza
| 170
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- Lead erosion in permanent pacemaker: A cumbersome complication
- Bakhtawar Shah, Zahid
Aslam Awan, Tahmeedullah, Zahoor Ahmed Khan
| 174 |
- A clinical study of ectopic pregnancy
- Najma Bano Shaikh,
Shabnam Shaikh, Farhana Shaikh
| 178 |
- Helicobacter
pylori prevalence and histopathological findings in
dyspeptic patients
- Khalid Mehmood, Abdul
Aleem Awan, Naveed Muhammad, Fariha Hasan, Abdul Nadir
| 182
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- Vitamin-D status at breast cancer diagnosis: Correlation with social and
environmental factors and dietary intake
- Saba Imtiaz, Neelam Siddiqui
| 186 |
- Frequency of gall bladder carcinoma in patients with
acute and chronic cholecystitis
- Najamul Haq, Basharat
Ali Khan, Muhammad Imran, Adeel Akram, Abdul Basit Jamal, Fatima Bangash
| 191
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- Prevalence of metabolic syndrome and its component abnormalities among
school age Pakistani children
- Amina Zehra Iqbal,
Sarah Basharat, Adeel Basharat, Shifa Basharat
| 194 |
- Variation in lung volumes and capacities among young
males in relation to height
- Urooj Bhatti,
Keenjher Rani, Muhammad Qasim Memon
| 200 |
- Association between psoriasis and coeliac disease
related antibodies
- Jauhar Mumtaz Khan,
Sibghat Ullah Rao, Muhammad Usman Rathore, Wasif Janjua
| 203
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- Morphometrical analysis of intervillous space and
villous membrane thickness in maternal anaemia
- Nazma Kiran, Alia
Zubair, Henna Khalid, Ambreen Zafar
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207
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- Treatment of
chronic hepatitis-C with standard interferon and ribavirin
- Shakeel Ahmad Jadoon, Habib Ahmad Jadoon, Hasan Shahzad Nazar
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212
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- Endoscopic findings in patients presenting with
oesophageal dysphagia
- Adil Naseer Khan,
Khalid Said, Mukhtar Ahmad, Kishwar Ali, Rania Hidayat, HumeraLatif
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216
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- Comparison
of perinatal outcome in growth restricted fetuses retaining normal
umbilical artery Doppler flow to those with diminished or severely
reduced/absent end-diastolic flow
- Tariq Saeed Siddiqui,
Aisha Asim, Shafqut Ali, Tahir Saeed Siddiqui, Asima Tariq
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221
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- Laparoscopic cholecystectomy: Experience at a tertiary
level hospital
- Muhammad Tanveer Sajid, Syed Mukarram Hussain, Riaz Anwar Bashir, Quratul
Ain Mustafa, Muhammad Ahmed, Abdul Halim, Irfan Shukr, Muhammad Ahmed
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225
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- Problems of group dynamics in problem based learning
sessions
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Zafar Ahmed
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230
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- Frequency of modifiable risk factors in stroke
patients
- Muhammad Zuhaid, Salman, Javed Akhtar Chawla, Umer Farooq, Aamir
Ahmad, Saminullah Khan, Momina Asfandiyar
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235
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REVIEW ARTICLE
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- Functional status of vascular endothelium in diabetes mellitus
- Muhammad Saboor,
Moinuddin, Muhammad Ajmal, Samina Ilyas
| 239
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CASE REPORTS |
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- Giant ovarian cyst–An unusual finding
- Mukhtar Mehboob,
Samina Naz, Muhammad Zubair, Muhammad Ashraf Kasi
| 244
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- Impact of prosthodontic treatment on the oral health
related quality of life in a maxillectomy patient with multiple impairments
- Muhammad Faheemuddin,
Nazia Yazdanie, Muhammad Sohaib Nawaz
| 246
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- Fibroma of the tendon sheath-A rare hand tumour
following repetitive trauma to the palm
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Muhammad Yousaf
| 252
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- Role of isotretinion in cancer prevention and management in malignancies
associated with xeroderma pigmentosum
- Sajid Zaman, Jawad A
Gillani, Nabeela, Rauf Khattak, Iqbal, Noor ul Ain, Zanaib, Fayyaz
| 255 |
- Ureteral triplication and contralateral duplication with vesicoureteral
reflux
- Sohrab Naushad Ali, Aymon Naushad Ali, Niqad Ahmad,
Mian Naushad Ali
| 258
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GUIDELINES FOR
AUTHORS |
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©Copyrights
reserved.No part of this publication may be reproduced in any shape, form, or media without prior
permission of the editors. |
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Current Issue
Hypothyroidism
presenting as Hoffman Syndrome
A 40 year old male presented with
features suggestive of myxedema in the form of hoarseness of voice,
fatigability, constipation, cold intolerance, non-pitting bilateral ankle edema
and proximal muscle weakness from last 1.5 years. He was not a known diabetic
and hypertensive. On examination, he had bilateral calf muscle hypertrophy with
normal tone (photograph) along with percussion myoedema and delayed tendon jerk
relaxation. His thyroid profile showed T3 0.2 ng/ml, T4 10 ng/ml and TSH 135
mU/ml. Anti-microbial antibody and anti-thyroglobulin titers were 210 AU/ml and
425 U/ml respectively. Ultrasound thyroid showed atrophy. CPK was 450 U/l.
Electromyogram revealed polyphasic action potential consistent with hypothyroid
myopathy. Nerve conduction velocity was normal. Muscle biopsy revealed atrophy
of muscle fibers with increased inter-fiber ground substance. In this patient
having features of myxedema and bilateral calf muscle pseudohypertrophy, a
diagnosis of Hoffman syndrome was made and the patient responded to L-thyroxin
therapy.
In
hypothyroidism skeletal muscle atrophy usually occurs in the form of diffuse
myalgia, weakness, stiffness with slowness of both contraction and relaxation
phases of deep tendon reflexes. However calf muscle
pseudohypertrophy, myoedema and wasting are rarely encountered. Prominent
muscle pseudohypertrophy in adults is known as Hoffman syndrome. Definitive
diagnosis is made on muscle biopsy. Therapy with thyroxin corrects these muscle
abnormalities.
N.S.NEKI,
Professor,
Department of Medicine, Govt Medical College/GND Hospital, Amritsar, India,
143001.
- Cell: +91-9501029128.
- Email: drneki123@gmail.com
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